Medicaments containing acyclovir

Medicaments contenant acyclovir

Abstract

The invention relates to a topical pharmaceutical formulation suitable for use in treating virus infections of the skin and mucosa, and in particular it relates to topical aqueous gel formulations containing 9-(2-hydroxyethoxymethyl)guanine, otherwise known as aciclovir, that exhibit the required stability and allow flux of the compound into the skin.
L'invention concerne une formulation pharmaceutique topique servant à traiter des infections virales de la peau et des muqueuses et, en particulier, des formulations topiques de gel aqueux contenant 9-(2-hydroxyéthoxyméthyl)guanine, connue sous le non d'aciclovir, présentant la stabilité requise et permettant au composé de s'écouler vers l'intérieur de la peau.

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Patent Citations (7)

    Publication numberPublication dateAssigneeTitle
    DE-4425322-A1January 25, 1996Merck Patent GmbhVirostatika in hydrophober Gelgrundlage
    EP-0044543-A1January 27, 1982The Wellcome Foundation LimitedTopical formulations of 9-(2-hydroxyethoxymethyl) guanine
    EP-0551626-A1July 21, 1993LEK, tovarna farmacevtskih in kemicnih izdelkov, d.d.Thermoreversible gel as a liquid pharmaceutical carrier for a galenic formulation
    EP-0614659-A2September 14, 1994Taro Pharmaceutical Industries LimitedPharmaceutical compositions in semisolid form and a device for administration thereof
    EP-0679390-A2November 02, 1995Zyma SAAufsprühbare pharmazeutische Zubereitungen für die topische Anwendung
    EP-0733357-A1September 25, 1996Dompé S.P.A.Pharmaceutical formulations in form of thixotropic gel
    WO-9734607-A1September 25, 1997Glaxo Group LimitedTopical formulations of aciclovir

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